Hepatitis D Virus (HDV) RNA, Quantitative PCR

Alphabetical Test listing

Hepatitis D Virus (HDV) RNA, Quantitative PCR-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

HDV PCR
HDV RNA Quantitation
Hepatitis D Quant
Hepatitis Delta
HDV viral load
HDV

Useful for:

This assay is used to determine the number of international units (IU) of hepatitis D virus (HDV) RNA per milliliter in serum or plasma in known HDV-positive patients.

Specimen type:

Serum

Collection container:

Red serum vial/tube - 5 mL

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot a minimum of 30 minutes
Spin within 24 hours of sample collection
Transfer serum to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as serum

Transport container:

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Transport and stability:

Frozen (preferred) – 14 days

Freeze/thaw cycles - stable x3

Refrigerated – 14 days

Ambient – 3 days

Reason for rejection:

Gross hemolysis, lipemia or visible microbial contamination
Frozen glass tubes

Performing lab:

Labcorp (550653): R-NX

TAT:

4 - 7 days

Method:

Reverse transcription-quantitative polymerase chain reaction (RT-qPCR)

Reference ranges:

Not detected: < 20 IU/mL

Assay range: 20 - 2,000,000 IU/mL

Clinical information:

Hepatitis D virus (HDV) is an incomplete RNA virus that requires the helper function of Hepatitis B virus (HBV) envelope proteins (HBSAg) to replicate. The HDV Real-time RT-PCR assay detects HDV RNA in serum or plasma

CPT codes:

87523

Date created:

01/13/2022

Revised date:

03/04/2026

Review date:

03/04/2026