Hepatitis D virus antibody, IgG and IgM

Alphabetical Test listing

Hepatitis D virus antibody, IgG and IgM-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

HDV
Hepatitis delta
Hepatitis D total antibody

Useful for:

Hepatitis D virus (HDV) is an incomplete RNA virus that requires the helper function of Hepatitis B virus (HBV) envelope proteins (HBSAg) to replicate. The presence of HDV antibodies indicates exposure to HDV, but does not distinguish acute or chronic HDV infection. Typically the disappearance of HDV antibodies is indicative of resolution of infection.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum
Freeze

Transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (preferred) – 14 days

Refrigerated – 14 days

Frozen – 14 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Gross hemolysis or lipemia
Visible microbial contamination
Heat-inactivated samples

Performing lab:

Labcorp (144012); R-NX

Days set up:

Daily

TAT:

6 days

Method:

The HDV total antibody ELISA is a competitive immunoassay.

Anti-HDV antibodies, if present, compete with HRP-conjugated polyclonal anti-HDV antibodies for recombinant HDV antigen adsorbed to the microtiter plate.

Reference ranges:

Negative

CPT codes:

86692

Date created:

01/13/2022

Revised date:

06/25/2024

Review date:

01/09/2024