Therapeutic drug management
Trough levels are most reproducible
Dk green heparin (Li or Na), no gel
Immediatley following collection, mix sample by gentle inversion, 5 - 10 times
Refrigerated (preferred)
Ambient - 3 days
Frozen (OK)
Gel-barrier tubes are not recommended
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Serum atenolol concentrations producing beta-blockade: 200 - 500 ng/mL
Trough levels are most reproducible
Not established