CNS Demyelinating disease evaluation, serum
CNS Demyelinating disease evaluation, serum-994
AQP4
Aquaporin
Devic's Antibody
NMO (Neuromyelitis Optica)
NMO-IgG
Optic Neuritis Antibody
Transverse Myelitis Antibody
Vision Loss Antibody
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Diagnosis of inflammatory demyelinating diseases (IDDs) with similar phenotype to neuromyelitis optica spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis
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Diagnosis of autoimmune myelin oligodendrocyte glycoprotein-opathy
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Diagnosis of neuromyelitis optica
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Distinguishing NMOSD, acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis from multiple sclerosis early in the course of disease
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Diagnosis of ADEM
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Prediction of a relapsing disease course
For optimal antibody detection, recommend blood collection to occur before initiation of immunosuppressant medication.
Immediately following collection, thoroughly mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
- Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
Refrigerated (preferred) - 28 days
Frozen - 28 days
Ambient - 72 hours
Gross hemolysis, lipemai or icterus
Flow Cytometry
Negative
86363
86256 X2 (if appropriate)