Therapeutic drug management
Dk green heparin (Li or Na), no gel
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting
Refrigerated (preferred)
Ambient (OK) - 3 days
Frozen (OK)
Gel-barrier tubes are not recommended
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Clozapine: 350 - 600 ng/mL
Clozapine & Norclozapine (combined total): >450 ng/mL