Dysautonomia, Autoimmune/Paraneoplastic Evaluation, Serum

Alphabetical Test listing

Dysautonomia, Autoimmune/Paraneoplastic Evaluation, Serum-14899

  
Dysautonomia, Autoimmune/Paraneoplastic Evaluation, Serum
  
14899
  
LAB14899
  
DYS2
  
ANNA (Antineuronal Nuclear Antibody)
Anti-CV2
Anti-Enteric Neuronal Antibody
Anti-Hu
Antineuronal
Cerebellar Antibodies
Chorea
Collapsin Response-Mediator Protein-5 Antibody (CRMP-5), Serum
Cramp-fasciculation
Dorsal Root Ganglion Antibody
DPPX
Hu Antibody
Isaacs disease
Motor End-Plate Antibody
Motor Nerve Terminal Antibodies Myoid Antibody
Neuromuscular hyperexcitability
Neuromyotonia
Neuronal ganglionic acetylcholine receptor antibody
Neuronal Nuclear Antibody Panel
Neuronal-Anti
Paraneoplastic Antibodies
Paraneoplastic Autoantibody Evaluation
Paraneoplastic
Neurological
Autoimmunity
Dipeptidyl aminopeptidase-like protein 6
  
Dysautonomia, Interpretation, S
AChR Ganglionic Neuronal Ab, S
Anti-Neuronal Nuclear Ab, Type 1
AP3B2 IFA, S
CRMP-5-IgG, S
CASPR2-IgG CBA, S
DPPIS DPPX Ab IFA, S
LGI1-IgG CBA, S
Purkinje Cell Cytoplasmic Ab Type 2

For reflex tests, see algorithm listed on Clinical and Interpretive info tab
  
Serum
  

Gold serum separator (SST) tube x 2

  
4.0 mL
  
2.5 mL
  

Immediately following collection, mix sample thoroughly by gentle inversion, 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  

Screw cap transfer vial/tube (Mayo T914)

  

Red serum vial/tube, 5 mL x 2

Red serum vial/tube, 10 mL

  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum, within two (2) hours of sample collection
  

Refrigerated (preferred) – 28 days

Ambient – 72 hours

Frozen – 28 days

  
28 days
  
  • Gross hemolysis
  • Gross lipemia
  • Gross icterus
  
Mayo Clinic Laboratories (DYS2): R-NX
  
Mo - Su
Reflex tests: Varies
  
8 - 12 days
  

Immunofluorescence assay (IFA)

Cell Binding Assay (CBA)

Western Blot (WB), Immunoblot (IB)

Radioimmunoassay (RIA)

  

See report

  

Utilization guidelines for neurologic autoimmune panels

 

  
Negative results do not exclude autoimmune dysautonomia or cancer.

Intravenous immunoglobulin (IVIg) treatment prior to the serum collection may cause a false-positive result.
  
83519
86255 x 7

Additional CPT codes (if appropriate):
84182 AN1BS
86256 AN1TS
84182 AN2BS
86255 APBCS
86256 APBTS
86256 CRMTS
84182 CRMWS
86255 DPPCS
86256 DPPTS
86256 PC2TS
  
02/22/2022
  
05/01/2023
  
05/01/2023