Apixaban anti-Xa

Alphabetical Test listing

Apixaban anti-Xa-994

Test name:

Apixaban anti-Xa

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Eliquis

Useful for:

To measure plasma apixaban concentration in ng/mL.

Specimen type:

Sodium citrate (Na cit) plasma

Collection container:

Lt blue Sodium citrate (NaCit)

Volume:

1.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediatley following collection, mix sample by gentle inversion 3 - 4 times to prevent clotting

Processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as Na citrate plasma
Freeze within six (6) hours of sample collection

Transport container:

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Transport and stability:

Frozen (preferred)

Freeze/thaw cycles: stable x6

Ambient - 6 hours

Reason for rejection:

Gross hemolysis
Gross lipemia

Performing lab:

LabCorp Burlington (504385): R-NX

Days set up:

Mo - Fr

TAT:

2 - 5 days

Method:

Chromogenic anti-Xa. Apixaban inhibition of factor Xa (present in excess). Residual Xa is measured using a chromogen and is inversely proportional to the apixaban present.

Clinical information:

Although routine monitoring is not needed, there are a number of clinical circumstances in which clinicians want or need to know a patient's Apixaban level. Levels can be accurately and precisely measured using either a chromogenic anti-Xa assay or LC/MS-MS.

CPT codes:

85130

Date created:

08/29/2019

Revised date:

12/31/2023

Review date:

12/31/2023