Cytokeratin AE1-AE3 by IHC

Alphabetical Test listing

Cytokeratin AE1-AE3 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

CK AE1-AE3

Tests included:

All IHC stains will include a positive control tissue

Useful for:

This antibody is best used as part of an antibody cocktail (created in our lab) with cytokeratins CAM5.2 and MAK6; this antibody cocktail is called "Cytokeratin cocktail or CK cocktail"
When used in a cocktail, this cocktail can identify most cytokeratins

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin-embedded tissue

Transport container:

Formalin-fixed, paraffin-embedded (FFPE) tissue block

Alternate transport container:

FFPE tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

AE1-AE3 is an antibody cocktail that identifies the following high molecular weight keratins (56.5, 50, 48, 40; 65-67, 64, 59, 58, 56 kD)
AE1-AE3 is part of the antibody cocktail termed "CK cocktail" in our lab (see below)

Staining pattern

Cytoplasmic

References

Moll et. al.; The Catalog of Human Cytokeratins: Patterns of Expression in Normal Epithelia, Tumors and Cultured Cells; Cell 31:11-24, 1982.

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

10/30/2017

Revised date:

10/18/2018

Review date:

01/12/2024