Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum

Alphabetical Test listing

Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum-994

  
Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Serum
  
994
  
LAB994
  
MSO
  
Encephalitis
Myelitis
Encephalopathy
Myelopathy, pediatric
Myelopathy, child
  
PCSI Peds Autoimmune CNS Interp, S
Anti-Neuronal Nuclear Ab, Type 1
CASPR2-IgG CBA, S
DPPX Ab IFA, S
GABA-B-R Ab CBA, S
GAD65 Ab Assay, S
GFAP IFA, S
LGI1-IgG CBA, S
mGluR1 Ab IFA, S
MOG FACS, S
Neurochondrin IFA, S
NMDA-R Ab CBA, S
NMO/AQP4 FACS, S
Purkinje Cell Cytoplasmic Ab Type Tr

For reflex tests, see algorithm on Clinical and Interpretive info tab
  

 

Evaluating children with autoimmune central nervous system disorders using serum specimens

  
  • For optimal antibody detection, specimen collection is recommended prior to initiation of immunosuppressant medication or intravenous immunoglobulin treatment.
  • This test should not be requested for patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference.
  
Serum
  

Red serum vial/tube, 10 mL

  
4 mL
  
2 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Centrifuge within two (2) hours of sample collection
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  

Screw cap transfer vial/tube (Mayo T914)

  

Gold serum separator (SST) tube

  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Centrifuge within two (2) hours of sample collection
  3. Transfer serum to a Screw cap transfer vial/tube (Mayo T914), labelled as serum
  

Screw cap transfer vial/tube (Mayo T914)

  

Refrigerated (preferred) – 28 days

Ambient – 72 hours

Frozen – 28 days

  
28 days
  
Mayo Clinic Laboratories (PCDES): R-NX
  
Varies
  
8 - 12 days
  

Immunofluorescence assay (IFA)

Cell-binding assay (CBA)

Fluorescence activated cell sorting assay (FACS)

Radioimmunoassay (RIA)

Immunoblot (IB)

  
86341
86363
86053
86255 x 10

Additional CPT codes (if appropriate):
84182 AN1BS
86256 AN1TS
84182 AN2BS
86255 DPPCS
86256 DPPTS
86256 GABIS
86255 GFACS
86256 GFATS
86255 GL1CS
86256 GL1TS
86363 MOGTS
86255 NCDCS
86256 NCDTS
86256 NMDIS
86053 NMOTS
84182 PCTBS
86256 PCTTS
  
03/17/2023
  
03/20/2023
  
03/20/2023