Lacosamide

Alphabetical Test listing

Lacosamide-8533

Test name:

Lacosamide

Test number:

8533

Excellian order number:

LAB8533

Abbreviation:

LCS

Alternate names:

Vimpat

Tests included:

Lacosamide
Desmethyllacosamide

Useful for:

Lacosamide is a functional amino acid specifically synthesized as an anticonvulsant drug. In addition to being approved for use as adjunctive therapy in the treatment of partial-onset seizures, it is being investigated as a treatment for diabetic neuropathic pain.

Specimen type:

Serum

Collection container:

Red serum vial/tube - 5 mL

Volume:

0.25 mL

Minimum volume:

0.1 mL
Submission of the minimum volume does not allow for repeat testing

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Alternate specimen type:

EDTA plasma
Heparin plasma

Alternate collection container:

Lavender (EDTA), 4mL

Dk green heparin (Li or Na), no gel

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

Alternate processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to aTransfer vial/tube with cap - 12mL (LabCorp), labelled as the appropriate plasma type

Transport and stability:

Ambient (preferred) - 14 days

Refrigerated -14 days

Frozen - 105 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Gel-barrier tubes

Performing lab:

LabCorp (007012): R-LC

Days set up:

Mo - Fr

TAT:

5 days

Method:

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference ranges:

5.0 - 10.0 µg/mL

CPT codes:

80235

Date created:

07/01/2010

Revised date:

12/20/2023

Review date:

12/20/2023