Anti-Jo-1

Alphabetical Test listing

Anti-Jo-1-13408

Test name:

Anti-Jo-1

Test number:

13408

Excellian order number:

LAB13408

Abbreviation:

JO1

Alternate names:

Polymyositis
t-RNA synthetase

Useful for:

Evaluate patients suspected of having polymyositis, dermatomyositis, or polymyositis-scleroderma overlap syndrome.

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

0.6 mL

Minimum volume:

0.3 mL

Collection instructions:

Immediatley following collection, mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot for a minimum of 30 minutes
Spin within two (2) hours of sample collection

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x 3

Reason for rejection:

Hemolysis
Icterus
Lipemia
Bacterial contamination

Performing lab:

LabCorp Burlington (161455): R-LC

Days set up:

Mo - Sa

TAT:

1 - 3 days

Method:

Multiplex flow immunoassay

Reference ranges:

0.0 - 0.9 AI

Clinical information:

Anti-Jo-1 antibodies are present in approximately 20% to 30% of patients with adult-onset polymyositis syndromes. They are present in >65% of patients with both myositis and interstitial lung disease. In such patients, the presence of anti-Jo-1 antibodies may be predictive of a response to steroid treatment. Testing for ANAs is not adequate for the detection of anti-Jo-1 antibodies.

CPT codes:

86235

LOINC code:

Result 11565-9

Date created:

03/27/2019

Revised date:

03/29/2021

Review date:

12/31/2023