HIV-1 PhenoSense®

Alphabetical Test listing

HIV-1 PhenoSense®-13572

Test name:

HIV-1 PhenoSense®

Test number:

13572

Excellian order number:

LAB13572

Abbreviation:

PHENOSENSE

Alternate names:

HIV-1 resistance testing
Human immunodeficiency virus 1 (HIV-1) PhenoSense
PhenosenseTM
Phenotyping

Useful for:

Determines viral phenotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors(NRTI), nonnucleoside reverse transcriptase inhibitors(NNRTI), and protease inhibitors (PI). Viral replication capacity is also included.

Limitations:

This procedure should be used for patients with documented HIV-1 infection and viral loads ≥500 copies/mL.

Specimen type:

EDTA plasma

Collection container:

Lavender (EDTA), 4mL x 2

Volume:

3.0 mL

Collection instructions:

Collect specimen in two (2) lavender-top (EDTA) tubes
Immediately following collection, mix sample thoroughly by gently inverting 8 - 10, times to prevent clotting

Processing instructions:

Spin within six (6) hours of sample collection
Transfer plasma to a Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp), labelled as EDTA plasma
Freeze

Transport container:

Screw-cap polypropylene frozen transport vial/tube - 4mL (LabCorp)

Transport and stability:

Frozen

Reason for rejection:

Insufficient volume
Heparinized plasma
Non-frozen specimens
Specimens exposed to repeated freeze/thaw cycles
Specimen received in "pop-top" or "snap-cap" tube
Specimen collected in green-top (heparin) tubes

Performing lab:

Monogram Biosciences (V3200) via LabCorp (551800): R-LC

TAT:

16 - 22 days

Method:

Polymerase chain reaction (PCR) amplification and viral culture

Reference ranges:

An interpretive report will be provided

CPT codes:

87903
87904 x 12

LOINC code:

Result 45182-3

Date created:

04/08/2019

Revised date:

01/03/2024

Review date:

01/03/2024