Therapeutic drug management
Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting
Ambient (preferred) - 3 days
For storage beyond three days, specimen should be refrigerated or frozen.
Refrigerated (OK)
Frozen (OK)
Gas chromatography/flame ionization detection (GC/FID)
Therapeutic and toxic ranges have not been established
Usual therapeutic doses produce mitotane serum concentrations of less than 100 µg/mL