Beta F1 by IHC

Alphabetical Test listing

Beta F1 by IHC-12376 - Technical only, 12379 - Technical & interpretation

Test name:

Beta F1 by IHC

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Alternate names:

Beta framework
BF-1

Tests included:

All IHC stains will include a positive control tissue

Useful for:

Useful in identifying alpha-beta T-cell receptors from T-cell clones or polyclonal populations of T-cells
Aids in diagnosing T-cell lineage neoplasms

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin embedded tissue block

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Alternate transport container:

Tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Unlabeled/mislabeled block
Insufficient tissue
Slides broken beyond repair

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

Recognizes T-cell receptor (TCR) beta subunit, that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules
TCR is composed of a heterodimer; 95% of T cells this consists of an alpha and beta chain and 5% of T cells this consists of gamma and delta chains

Staining pattern

Cytoplasmic

References

Ohshima K et al: Virchows Arch. 1999 Aug;435(2):92-100.

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

10/30/2017

Revised date:

10/17/2018

Review date:

01/12/2024