Synaptophysin by IHC

Alphabetical Test listing

Test name:

Test number:

12376 - Technical only, 12379 - Technical & interpretation

Excellian order number:

LAB12376
LAB12379

Tests included:

Useful for:

Use in a panel for neuroendocrine tumors
Other neuroendocrine markers include chromogranin, Leu-7 (and NSE)
Synaptophysin is more specific than NSE and has not been detected in non-neuroendocrine cells
Synaptophysin is usually used in combination with chromogranin to increase the sensitivity

Specimen type:

Tissue

Processing instructions:

Submit a formalin-fixed, paraffin embedded tissue block

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Alternate processing instructions:

FFPE tissue section mounted on a charged, unstained slide

Transport and stability:

Ambient (preferred)

Reason for rejection:

Performing lab:

AHL - Immunohistochemistry

Days set up:

Mo - Fr

TAT:

1 - 2 days

Method:

Immunohistochemical staining and microscopic examination

Reference ranges:

If requested, an interpretive report will be provided

Clinical information:

Specifications

Synaptophysin is a glycoprotein present in pre-synaptic vesicles of neurons, and in neurosecretory granules of neuroendocrine cells

Staining pattern

CPT codes:

88342 - 1st stain
88341 - each additional stain

Date created:

09/13/2017

Revised date:

10/17/2018

Review date:

01/12/2024