Plasminogen activator inhibitor 1 (PAI-1) 4G/5G polymorphism

Alphabetical Test listing

Plasminogen activator inhibitor 1 (PAI-1) 4G/5G polymorphism-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Plasminogen activator inhibitor (PAI-1)
Gene polymorphism
PAI-1 4G/5G Polymorphism

Useful for:

Deep vein thrombosis (DVT) and coronary artery disease (CAD) are associated with increased PAI-1 levels. Elevated PAI-1 levels may help predict risk of reinfarction in survivors of myocardial infarction, particularly in young individuals. PAI-1 levels tend to be lower in individuals with 4G/5G or 5G/5G genotype compared to a 4G/4G genotype.

Specimen type:

EDTA whole blood

Collection container:

Lavender (EDTA), 4mL

Volume:

1.0 mL

Collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

Transport container:

Lavender (EDTA), 4mL

Alternate specimen type:

ACD whole blood

Alternate collection container:

Yellow ACD (A or B)

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting

Alternate transport container:

Yellow ACD (A or B)

Required forms/information:

Molecular Medicare Billing Request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medicare billing request form to notify us of the need for Allina Health Laboratory to bill insurance.

Transport and stability:

Ambient (preferred) - 8 days

Refrigerated - 8 days

Performing lab:

Esoterix Coagulation Lab (129100) via LabCorp (500309): R-NX

Days set up:

Mo, Th

TAT:

7 - 11 days

Method:

Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) technologies

Reference ranges:

An interpretive report will be provided

Preauthorization:

This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.

CPT codes:

81400

Subject to medical necessity (Y/N):

Yes

LOINC code:

Result UNLOINC

Other billing information:

Medical necessity

Molecular Medicare Billing Request

Date created:

05/24/2019

Revised date:

05/23/2024

Review date:

08/18/2022