HIV-1/HIV-2 antibody differentiation test *
HIV-1/HIV-2 antibody differentiation test *-12510
HIV confirm
Only available as reflex test for Reactive HIV 1/2 Ag/Ab (H12)
Only available as reflex test for reactive HIV 1/2 Ag/Ab (H12)
Immediately following collection, thoroughly mix sample by gently inverting 5 times
- Allow sample to clot for a minimum of 30 minutes
- Spin within two (2) hours of sample collection
Gold serum separator (SST) tube
EDTA plasma
Immediately following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting
Lt green:
Spin within two (2) hours of sample collection
Dk green/lavender:
- Spin
- Transfer plasma to a False bottom plasma/serum transport vial/tube (AHL), labelled as the appropriate plasma type, within two (2) hours of sample collection
False bottom plasma/serum transport vial/tube (AHL)
Refrigerated - 7 days
- Improper labels (unlabeled or mislabeled)
- Hemolysis (some procedures)
- Improper anticoagulant or ratio
- Delay in transport
- Improper storage temperature affecting results
- Inappropriate timing of collection
- Improper container
- Leaking container resulting in compromised specimen
- Quantity not sufficient (QNS)
Immunochromatographic
Non-reactive
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HIV-1/HIV-2 Differentiation Assay results: |
HIV-1 |
HIV-2 |
Interpretation |
|
Positive |
Non-reactive |
Positive for HIV-1 Antibodies. Suggest follow-up testing: HIV-1 RNA Quant (7867/LAB7867) |
|
|
Non-reactive |
Positive |
Positive for HIV-2 Antibodies. Suggest follow-up testing: HIV-2 DNA (Mayo Clinic Laboratories) |
|
|
Non-reactive |
Non-reactive |
HIV Ag/Ab combo test is positive, presumably due to presence of HIV p24 Ag, non-reactive for both HIV-1 and HIV-2 antibodies, Suggest follow-up testing: HIV-1 RNA Quant (7867/LAB7867) |
|
|
Indeterminate |
Indeterminate |
HIV Ag/Ab combo test is positive, possibly due to presence of HIV p24 Ag as differentiation assay is indeterminate for both HIV-1 and HIV-2 antibodies, Suggest follow-up testing: HIV-1 RNA Quant (7867/LAB7867) |
|
|
Indeterminate |
Positive |
Indeterminate for HIV-1 and positive for HIV-2, Suggest follow-up testing: HIV-1 RNA Quant (7867LAB7867), HIV-2 DNA (994/LAB994, Mayo Clinic Laboratories) |
|
|
Positive |
Indeterminate |
Indeterminate for HIV-2 and positive for HIV-1, Suggest follow-up testing: HIV-1 RNA Quant (7867/LAB7867) |
|
|
Positive |
Positive |
HIV positive but undifferentiated, additional testing recommended Suggest follow-up testing: HIV-1 RNA Quant (HVL) Positive for HIV-2 Antibodies, HIV-2 DNA (994/LAB9994, Mayo Clinic Laboratories) |
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