Samples should not be taken from patients receiving therapy with high biotin doses (i.e. > 5 mg/day) until at least 8 hours following the last biotin administration.
Immediately following collection, thoroughly mix sample by gently inverting 5 times
Gold:
Red:
Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting
Lt green plasma separator (PST)
Refrigerated (preferred) -14 days
Ambient - 5 days
Frozen - 1 year
Electrochemiluminescence immunoassay (ECLIA)
Age and sex specific
1 week - 4 weeks | 31.6 - 431 ug/dl |
1 month - 12 months | 3.4 - 124 ug/dl |
1 year - 4 years | 0.47 - 19.4 ug/dl |
5 years - 10 years | 2.8 - 85.2 ug/dl |
Age | Female | Male |
10 - 14 yrs | 33.9 - 280 μg/dL | 24.4 - 247 μg/dL |
15 - 19 yrs | 65.1 - 368 μg/dL | 70.2 - 492 μg/dL |
20 - 24 yrs | 148 - 407 μg/dL | 211- 492 μg/dL |
25 - 34 yrs | 98.8 - 340 μg/dL | 160 - 449 μg/dL |
35 - 44 yrs | 60.9 - 337 μg/dL | 88.9 - 427 μg/dL |
45 - 54 yrs | 35.4 - 256 μg/dL | 44.3 - 331 μg/dL |
55 - 64 yrs | 18.9 - 205 μg/dL | 51.7 - 295 μg/dL |
65 - 74 yrs | 9.4 - 246 μg/dL | 33.6 - 249 μg/dL |
≥75 yrs | 120 - 154 μg/dL | 16.2 - 123 μg/dL |