Liver-Kidney Microsomal (LKM) antibodies

Alphabetical Test listing

Liver-Kidney Microsomal (LKM) antibodies-13414

  
Liver-Kidney Microsomal (LKM) antibodies
  
13414
  
LAB13414
  
LKMABY
  
LKM
LKM-1 antibodies
  

The detection of LKM-1 IgG Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2).

  
Serum
  
  
1.0 mL
  
0.3 mL
  

Immediately following collection, thoroughly mix sample by gently inverting 5 times

  
  1. Allow sample to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection
  

Gold serum separator (SST) tube

  
  
  1. Allow sample to clot
  2. Spin
  3. Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum, within two (2) hours of sample collection
  
  

Ambient (preferred)  - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles: stable x 4

 

  
  • Hemolysis
  • Lipemia
  • Gross bacterial contamination
  • Heat treated
  • Sample with preservative added
  
LabCorp Burlington (163980): R-LC
  
Tu, Th, Su
  
2 - 3 days
  

Enzyme-linked immunosorbent assay (ELISA)

  

Negative:      0.0 - 20.0

Equivocal:   20.1 - 24.9

Positive:   >24.9

  

The detection of LKM-1 IgG Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2). LKM Antibodies are markers of AIH2 which usually begins in childhood and generally affects children under 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2-14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.

  
86376
  
Result 32220-6
  
04/09/2019
  
04/07/2020
  
12/31/2023