Substance P is a neuropepetide present in the central and peripheral nervous system. Substance P is a neurotransmitter released in response to pain and other noxious stimuli. Substance P is a neuropeptide of the tachykinin class that also includes neurokinin. Substance P is found in the brain, spinal cord, and peripheral tissues and is released from nerve endings in response to stimuli. Increased substance P levels can occur in neurogenic inflammation and physiological stress and may be associated with carcinoid or neuroendocrine tumors.
Patient should be fasting 10-12 hours prior to collection.
Antacid medication or medication that may affect intestinal motility should be discontinued if possible for at least 48 hours prior to collection.
Immediatley following collection, mix sample by gently inverting 5 times
Frozen (strict) - 4 weeks
Refrigerated - NO
Ambient - NO
Specimens received refrigerated or room temperature
Enzyme Immunoassay (EIA)
<1700 pg/mL