Aspergillus galactomannan antigen detection, cerebrospinal fluid

Alphabetical Test listing

Aspergillus galactomannan antigen detection, cerebrospinal fluid-994

  
Aspergillus galactomannan antigen detection, cerebrospinal fluid
  
994
  
LAB994
  
MSO
  

Patients diagnosed with chronic granulomatous disease and/or Job's syndrome may yield a reduced detection of galactomannan.

  
Cerebrospinal fluid (CSF)
  

Sterile vial/container

  
2.0 mL
  
0.35 mL
Submitting the minimum volume does not allow for repeat testing
  

Collect specimen using aseptic technique

  
  • Avoid opening the specimen container after collection
  • Do NOT aliquot
  • Transport in sealed tubes
  

Sterile screw-cap, leak proof container

  

Refrigerated, Unopened (preferred) - 5 days

Refrigerated, Opened - 48 hours

Frozen - OK

  
LabCorp Burlington (183858): R-NX
  
Mo, We, Fr
  
2 - 10 days
  

Enzyme immunoassay (EIA)

  

Index 0.00 - 0.49

  

Reduced assay sensitivity may occur in patients receiving concomitant antifungal therapy. Penicillium species, Alternaria species, Paecilomyces species, Geotrichum species, and Histoplasma species have demonstrated reactivity with the monoclonal antibodies used in the assay and may, therefore, yield a positive test result. Positive results in patients with no clinical signs of disease have been reported, especially in young children. Most of these are considered to be false positives. Young children may have a positive assay result due to the presence of galactofuranaase contained in various foods (cereals) and milk. Patients receiving piperacillin/tazobactam or semisynthetic ?-lactamase therapy may have false-positive results. False-positive results may also occur with use of Plasma-Lyte for either intravenous hydration or BAL specimen collection.

  
87305
  
Result 53865-2
  
06/03/2019
  
06/03/2019