BRAF V600 mutation analysis

Alphabetical Test listing

BRAF V600 mutation analysis-12365

Test name:

Test number:

12365

Excellian order number:

LAB12365

Abbreviation:

BRAF

Alternate names:

v-raf murine sarcoma viral oncogene homolog B1

Useful for:

Identification of melanoma patients eligible for Vemurafenib treatment
Diagnostic, prognostic and possible therapeutic information for other types of tumors such as lung, colon, thyroid and brain

Specimen type:

Tumor specimen

Processing instructions:

Specimen should be formalin-fixed prior to embedding in paraffin.

Transport container:

Formalin-fixed, paraffin embedded (FFPE) tissue block

Required forms/information:

Molecular Medicare billing request

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
All information requested is required in order for your request to be completed

Transport and stability:

Ambient

Reason for rejection:

Samples fixed by means other than formalin fixation, such as B+, will not be accepted.
Decalcified bone specimens will not be accepted as this process degrades DNA.

Performing lab:

AHL - Molecular Diagnostics: D

Days set up:

Varies (weekly)

TAT:

5 - 7 days

Method:

Cobas 4800 BRAF V600 Mutation Test (IVD, Roche)

Reference ranges:

An interpretative report will be included

Clinical information:

Detection of a point mutation most commonly resulting in a V to E change at codon 600.

Preauthorization:

This test may require preauthorization from the insurance provider. Check the payer guidelines and, if needed, obtain the pre-authorization prior to sample collection.

CPT codes:

81210

Subject to medical necessity (Y/N):

Yes

Other billing information:

Medical necessity

Hospital clients submitting a request for this assay on an outpatient with Medicare should complete and submit a Molecular Medical billing request form along with the sample.

Complete and submit the form to notify us of the need for Allina Health Laboratory to bill insurance for Molecular testing performed
All information requested is required in order for your request to be completed

Molecular Medicare billing request

Date created:

08/08/2012

Revised date:

07/30/2018

Review date:

01/15/2024