Detection of point mutation (G to T mutation in exon 12 resulting in the V to F amino acid change at position 617) of the human JAK2 gene. This mutation is associated with myeloproliferative disorders.
Only ONE (1) tube needs to be drawn for any combination of the following tests:
Immediatley following collection, mix sample by inverting 8 - 10 times to prevent clotting.
Lavender (EDTA), 4mL
Submit specimen in original collection tube, unspun
Lt blue Sodium citrate (NaCit) - 2.7mL
Yellow ACD (A or B)
Multiplex, Allele-specific Polymerase Chain Reaction (AS-PCR) analyzed by capillary electrophoresis
An interpretive report will be included
The Calreticulin Exon 9 Assay can be ordered as a reflex to a negative JAK2 V617F Mutation Detection. If ordered as a reflex, do not order the individual assay.