P2Y12 inhibition

Alphabetical Test listing

P2Y12 inhibition-8816

  
P2Y12 inhibition
  
8816
  
LAB8816
  
P2Y
  
Clopidogrel (Plavix)
Platelet Inhibition
VerifyNow
  
Whole blood - P2Y12 collection kit
  
  

Direct venipuncture collection

  1. Using a 21 gauge needle or larger (butterfly is acceptable), collect tubes in the following order:
    1. One (1) clear top Vacutainer tube - partial fill 3 mL draw
    2. Three (3) blue Greiner tubes - These are partial fill 2 mL draw tubes. Fill exactly to the black arrow on the tube; do not over or under fill.
    3. One (1) lavender top tube
  2. Gently invert each tube 5 times.
  3. Additional tubes may be collected after these tubes have been collected.


Line draw collection

  1. Discard the first 5 mL of blood from the line.
  2. Ensure the catheter is free of clots.
  3. Immediately transfer blood in the following order:
    1. One (1) clear top Vacutainer tube - partial fill 3 mL draw
    2. Three (3) blue Greiner tubes - These are partial fill 2 mL draw tubes. Fill exactly to the black arrow on the tube; do not over or under fill.
    3. One (1) lavender top tube
  4. Gently invert each tube 5 times.
  5. Additional tubes may be collected after these tubes have been collected.
  

Submit collection tubes unspun  

 

  

Aspirin therapy and P2Y12 collection kit/tubes

  

TIME SENSITIVE - Send by STAT courier

Ambient - 4 hours

Hospital Draw - hand deliver to Lab; do not send thru Pneumatic Tube System (PTS).

  
  • Improper labeling (unlabeled or mislabeled)
  • Improper anticoagulant
  • Improperly filled tube
  • Hemolysis
  • Clotted specimen
  • Delay in transport
  • Improper storage/transport temperature
  
AHL - Coagulation: W
Available at the Central Laboratory, Mercy & United
  
Daily - 24 hours
  
1 hour
  

The VerifyNow point-of-care device is available for monitoring patients on anti-P2Y12 therapy (clopidogrel and prasugrel). The extent of ADP-induced platelet aggregation is recorded as the Platelet Reactivity Unit (PRU) value, which is diminished by thienopyridine agents that block the P2Y12 ADP receptor.

  

P2Y12 reaction units (PRU):

Patients on P2Y12 Inhibition therapy : <208
Patients not on P2Y12 Inhibitor medications: 180 - 376

  
85576
  
11/14/2011
  
01/13/2021
  
02/18/2020