N-methyl-D-aspartate receptor, CSF

Alphabetical Test listing

N-methyl-D-aspartate receptor, CSF-994

  
N-methyl-D-aspartate receptor, CSF
  
994
  
LAB994
  
MSO
  
Anti-NMDA CSF
anti-NR1
Glutamate receptor antibodies
N-methyl D-aspartate Ab CSF
NMDA R
NMDA receptor Ab CSF
  

If NMDA antibody IgG is positive, then a NMDA antibody is reported.

  
  • Confirm diagnosis of anti-NMDAR encephalitis.
  • May be used in monitoring treatment response in individuals who are antibody positive.
  
Cerebrospinal fluid (CSF)
  

Sterile vial/container

  
0.5mL
  
0.15mL
  

Sterile vial

  

Refrigerated (preferred) – 2 weeks

Ambient – 48 hours

Frozen – 1 year

  
  • Contaminated specimen
  • Hemolysis
  • Severe lipemia
  
ARUP (2005164) via LabCorp (820644): R-NX
  
Su - Sa
  
4 - 6 days
  

Semi-quantitative Immunofluorescence Assay (SQ-IFA)

  

< 1:1 titer

  

Anti-NMDA receptor IgG antibody is found in a subset of patients with autoimmune limbic encephalitis and may occur with or without associated tumor. Decreasing antibody levels may be associated with therapeutic response; therefore, clinical correlation must be strongly considered. A negative test result does not rule out a diagnosis of autoimmune limbic encephalitis.

  
86255
86256 (if indicated)
  
05/05/2020
  
01/31/2022
  
01/31/2022