B72.3 by IHC

Alphabetical Test listing

B72.3 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
B72.3 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
  • All IHC stains will include a positive control tissue
  
  • B72.3 reacts with a wide variety of adenocarcinomas, including ovarian, endocervix, endometrium, distal esophagus, stomach, colon, lung, breast, prostate, pancreas, and bile ducts
  • B72.3 does not react with hepatocellular carcinomas (0/20 cases)
  • Use B72.3 with panel in differentiating between malignant mesothelioma versus adenocarcinoma (see section on immunohistochemistry panels)
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

Tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • Reacts with a high molecular weight glycoprotein designated tumor-associated glycoprotein-72 (TAG-72)

 Staining patterns

  • Cytoplasmic and/or membrane/luminal staining

References

  1. Long et. al.: Reactivity of B72.3 with Adenocarcinomas an Immunohistochemical Study of 476 cases, Cancer 72:2495-8, 1993.
  
88342 - 1st stain
88341 - each additional stain
  
05/09/2017
  
10/17/2018
  
10/02/2020