ETV6 or TEL rearrangements are recurring abnormalities in B-cell ALL. According to current NCCN B-ALL guidelines, ETV6 rearrangements associated with ETV6/RUNX1 or TEL/AML abnormalities are classified as a good cytogenetic risk factor.
This test can be ordered individually or as part of the B-cell ALL FISH Panels. See the panel tests for more details.
Sterile cup or tube
Place specimen in a sterile cup/tube with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline.
Submit entire fresh specimen.
Sterile specimen cup/tube
Three 4-micron cut slides and one H&E stained slide
Touch prep slides
Note: Heavy metal fixatives are unacceptable.
AHL Cytogenetics Oncology Request
Fluorescence in situ hybridization (FISH)
Normal or Abnormal with interpretation