CD15 by IHC

Alphabetical Test listing

CD15 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
CD15 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
LeuM1
  
  • All IHC stains will include a positive control tissue
  
  • LeuM1 is useful in identifying Reed-Sternberg cells in classical Hodgkin's Disease (use with BERH2/CD30)
  • LeuM1 Reactivity:
Hodgkin's Disease:  
L & H Nodular HD 10% reactive
Classical HD 90 (60 - 100)
T cell lymphoma 20 (0 - 65)
B cell lymphoma <5
Myeloid leukemia 20 (5-100)
Carcinomas 50
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • LeuM1 reacts with an antigen on myelomonocytic cells (eosinophils, neutrophils, and basophils)
  • LeuM1 also reacts with Reed-Sternberg cells, activated T-cells, occasional large cell B and T cell NHLs and some AMLs and CMLs
  • LeuM1 labels majority of adenocarcinomas and may be only focally positive.

Staining pattern

  • Cell membrane, cytoplasmic and Golgi apparatus patterns (Golgi staining is often seen with Reed-Sternberg cells of classical Hodgkin's Disease).

  
88342 - 1st stain
88341 - each additional stain
  
05/15/2017
  
10/17/2018