CD15 by IHC

Alphabetical Test listing

CD15 by IHC-12376 - Technical only, 12379 - Technical & interpretation

CD15 by IHC
12376 - Technical only, 12379 - Technical & interpretation
  • All IHC stains will include a positive control tissue
  • LeuM1 is useful in identifying Reed-Sternberg cells in classical Hodgkin's Disease (use with BERH2/CD30)
  • LeuM1 Reactivity:
Hodgkin's Disease:  
L & H Nodular HD 10% reactive
Classical HD 90 (60 - 100)
T cell lymphoma 20 (0 - 65)
B cell lymphoma <5
Myeloid leukemia 20 (5-100)
Carcinomas 50

Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • LeuM1 reacts with an antigen on myelomonocytic cells (eosinophils, neutrophils, and basophils)
  • LeuM1 also reacts with Reed-Sternberg cells, activated T-cells, occasional large cell B and T cell NHLs and some AMLs and CMLs
  • LeuM1 labels majority of adenocarcinomas and may be only focally positive.

Staining pattern

  • Cell membrane, cytoplasmic and Golgi apparatus patterns (Golgi staining is often seen with Reed-Sternberg cells of classical Hodgkin's Disease).

88342 - 1st stain
88341 - each additional stain