RET Proto-oncogene, full gene analysis

Alphabetical Test listing

RET Proto-oncogene, full gene analysis-994

Test name:

Test number:

994

Excellian order number:

LAB994

Alternate names:

CCHS
Congenital central hypoventilation syndrome
Familial Medullary Thyroid Cancer
FMTC
Hirschsrpung Disease
Hirschsprung's Disease

Useful for:

Confirmation of suspected clinical diagnosis of multiple endocrine neoplasia type A or B, Hirschsprung disease, or congenital central hypoventilation syndrome in patients with a suspected diagnosis of any of these conditions

Patient preparation information:

A previous bone marrow transplant from an allogenic donor will interfere with testing.

Call 800-533-1710 for instructions for testing patients who have received a bone marrow transplant

Specimen type:

EDTA whole blood

Collection container:

Lavender (EDTA), 4mL

Volume:

3.0 mL

Minimum volume:

1.0 mL

Processing instructions:

Immediately after collection, mix tube thoroughly by gentle inversion to prevent clotting.

Submit specimen, unspun, in original tube.

Transport container:

Lavender (EDTA), 4mL

Alternate specimen type:

ACD whole blood

Alternate collection container:

Yellow ACD (A or B)

Alternate transport container:

Yellow ACD (A or B)

Required forms/information:

Molecular Genetics: Congenital Inherited Diseases Patient Information Form

Transport and stability:

Ambient (preferred) - 4 days

Refrigerated (OK)

Specimen preferred to arrive at Mayo within 96 hours of collection.

Performing lab:

Mayo Clinic Laboratories (RETZZ): R-NX

Days set up:

Varies/weekly

TAT:

3 - 4 weeks

Method:

Sequence Capture and Targeted Next-Generation Sequencing (NGS) followed by Polymerase Chain Reaction (PCR) and Sanger Sequencing

Reference ranges:

An interpretive report will be provided

CPT codes:

81406

Date created:

07/31/2015

Revised date:

11/18/2021