Ustekinumab and anti-Ustekinumab antibody

Alphabetical Test listing

Ustekinumab and anti-Ustekinumab antibody-994

Ustekinumab and anti-Ustekinumab antibody
Anti-interleukin antibody drug, Anti-IL12, IL23 inhibitor
Biologic monitoring, therapeutic drug monitoring (TDM)
Immunogenicity testing, an

Provides ustekinumab drug concentration and anti-ustekinumab antibodies in order to optimize treatment and facilitate clinical decision-making.

This assay may be helpful in any patients on ustekinumab therapy for Crohn's disease, psoriasis, or other autoimmune conditions.

3.0 mL
1.0 mL
Submitting the minimum volume does not allow for repeat testing
  1. Allow a minimum clotting time of 30 to 60 minutes
  2. Spin




Serum separator (SST) tube

EDTA plasma
Heparin plasma

Red serum vial/tube - 5 mL

Dk green heparin (Li or Na), no gel



  1. Allow a minimum clotting time of 30 to 60 minutes for the serum tube
  2. Spin and separate

Ambient (preferred) - 14 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles: Stable x 6

LabCorp Esoterix (504594): R-NX
1 day per week
11 - 25 days

Electrochemiluminescence immunoassay (ECLIA)


Ustekinumab: <0.1 μg/mL

  • Result ≥0.1 μg/mL indicates detection of ustekinumab
  • In the presence of anti-ustekinumab antibodies, the ustekinumab drug level reflects the free, antibody-unbound fraction of ustekinumab in serum.

Anti-ustekinumab antibody: <40 ng/mL

  • Result ≥40ng/mL indicates detection of anti-ustekinumab antibodies.