Clomipramine

Alphabetical Test listing

Clomipramine-447A

Test name:

Clomipramine

Test number:

447A

Excellian order number:

LAB447

Abbreviation:

CLM

Alternate names:

Anafranil

Tests included:

Desmethylclomipramine

Useful for:

Therapeutic drug management

Specimen type:

Serum

Collection container:

Red serum vial/tube, 5 mL

Volume:

2.0 mL

Minimum volume:

0.5 mL

Collection instructions:

Trough levels are most reproducible

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Serum/plasma transfer vial/tube (MedTox), labelled as serum

Transport container:

Serum/plasma transfer vial/tube (MedTox)

Alternate specimen type:

Heparin plasma

Alternate collection container:

Dk green heparin (Li or Na), no gel

Alternate collection instructions:

Immediately following collection, mix sample thoroughly by gently inverting 5 - 10 times, to prevent clotting

Alternate processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Serum/plasma transfer vial/tube (MedTox), labelled as the appropriate plasma type

Transport and stability:

Refrigerated (preferred)

Ambient - 3 days

Frozen (OK)

Reason for rejection:

Gel-barrier tubes are not recommended

Performing lab:

MedTox Laboratories (890): R-MX

Days set up:

Mo, We, Th, Fr, Su

TAT:

3 - 4 days

Method:

Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Reference ranges:

Clomipramine: none

Desmethylclomipramine: none

Clomipramine + Desmethylclomipramine: 230 - 450 ng/mL

Results that require action (critical):

Clomipramine: >400 ng/mL

Clomipramine + Desmethylclomipramine: >600 ng/mL

CPT codes:

G0480

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

11/30/2001

Revised date:

01/04/2024

Review date:

01/04/2024