Mycobacterium tuberculosis complex PCR

Alphabetical Test listing

Mycobacterium tuberculosis complex PCR-994

Mycobacterium tuberculosis complex PCR
Acid-Fast Bacilli (AFB)
AFB (Acid-Fast Bacilli)
Bacillus, Acid-Fast
MTB (Mycobacterium tuberculosis)
Mycobacterium tuberculosis (MTB)
TB (Tuberculosis)
Tubercle Bacilli: Mycobacterium tuberculosis
Tuberculosis (TB)
  • Rapid detection of Mycobacterium tuberculosis complex DNA, preferred method
  • Detection of M tuberculosis, when used in conjunction with mycobacterial culture
  • This test is for specimen sources other than sputum, BAL, blood and CSF
  • This test should not be usedto determine bacteriologic cure or to monitor response to therapy
  • This test is not intended for the detection of latent tuberculosis and must not be used as a substitute for tests intended for detection of latent tuberculosis such as the tuberculin skin test (TST/PPD) or an interferon gamma release assay (IGRA)
See collection instructions

See collection instructions

See collection instructions
See collection instructions

Submit only one (1) of the following specimens:

Body fluid (Body, bone marrow aspirate or ocular fluid)

Container/tube: Sterile container

Volume: 1 mL (minimum 0.5 mL)

Additional information: Only fresh, non-NALC/NaOH-digested body fluid is acceptable.


Container/tube: Sterile container

Volume: 10 g (minimum 5 g)

Additional information: Only fresh, non-NALC/NaOH-digested fecal specimens are acceptable.

Gastric washing

Container/tube: Sterile container

Volume: 2 mL (minimum 1 mL)

Collection Instructions: Neutralize specimen within 4 hours of collection with 20 mg of sodium carbonate per 2 mL of gastric washing.

Tissue  (Fresh tissue, bone, or bone marrow biopsy)

Container/tube: Sterile container

Volume: 10 mm (minimum 5 mm)

Collection instructions: Keep moist with sterile water or sterile saline

Additional information: Only fresh, non-NALC/NaOH-digested tissue is acceptable.

Urine, random

Container/tube: Sterile container

Volume: 1 mL (minimum 0.5 mL)


Submit specimen in the collection container

N-Nacetyl-L-cysteine (NALC)/NaOH [NALC/NaOH] digested respiratory specimens (Lavage fluid, bronchial washing, gastric washing, respiratory fluid, sputum, or tracheal secretion)

Sterile vial/tube

2 mL (minimum 1.0 mL)
  1. Submit digested specimen treated with NALC/NaOH.
  2. Clearly indicate on container and order form that specimen is a digested specimen.

Sterile vial/tube


Specimen source is required


Refrigerated (preferred) – 7 days

Ambient – NO

Frozen – 7 days

  • Blood
  • Specimen in anaerobe vial or viral transport medium (including but not limited to M4, M5, BD viral transport media, thioglycolate broth)
  • Swabs
  • Tissues in formalin
  • Specimens greater than 7 days old
Mayo Clinic Laboratories (MTBRP) via Labcorp (824009): R-NX
3 - 5 days

Real-Time Polymerase Chain Reaction (RT-PCR)


An interpretive report will be provided


Additional CPT codes (if appropriate):
87556 - Mycobacterium tuberculosis, complex, molecular detection, PCR
87015 - Mycobacteria culture, concentration (if appropriate)