Prostate specific antigen by IHC

Alphabetical Test listing

Prostate specific antigen by IHC-12376 - Technical only, 12379 - Technical & Interpretation

  
Prostate specific antigen by IHC
  
12376 - Technical only, 12379 - Technical & Interpretation
  
LAB12376
LAB12379
  
PSA
IHC
  
  • PSA is expressed by >99% of prostatic carcinomas (although poorly differentiated prostatic carcinomas may express this antigen weakly and/or focally)
  • PSA is a very durable antigen, even with prolonged formalin fixation
  • In vast majority of cases, prostatic acid phosphatase is not needed with PSA. However, we use prostatic acid phosphatase in weakly suspiciously PSA positive or PSA negative tumors in which prostatic origin is strongly suspected.
  
Tissue
  

Submit processed tissue block or tissue section mounted on a charged, unstained slide

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided.

  

All IHC stains will include a positive control tissue

Specifications:

  • PSA is a glycoprotein found in normal and neoplastic secretory and ductal prostatic epithelium

Staining pattern:

  • Cytoplasmic based staining.

  
88342 - 1 st stain
88341 - each additional stain
  
08/08/2017
  
10/19/2018