Screening test for Open Spina Bifida/ONTD (detects 80% Open Spina Bifida, 90% anencephaly), Trisomy 21/Down syndrome (detects 75 - 80%), and Trisomy 18/Edward's syndrome (detects 73%)
The gestational age for collection of the AFP tetra profile is 15.0 - 21.9 weeks for Downs syndrome, and 15.0 - 23.9 for Open Spina Bifida (optimal GA for Open Spina Bifida 16.0 - 18.9 weeks).
Specimens must be collected before amniocentesis.
Immediatley following collection, mix sample by gently inverting 5 times
Serum separator (Gold SST) tube
Ambient (preferred) - 7 days
Refrigerated - 14 days
Frozen - 14 days
Freeze/thaw cycles - stable x 3
Chemiluminescent immunoassay
An interpretive report will be provided