Human placental lactogen by IHC

Alphabetical Test listing

Human placental lactogen by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
Human placental lactogen by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
HPL
  
  • All IHC stains will include a positive control tissue
  
  • HPL is used to identify syncytiotrophoblastic cells of choriocarcinoma
  • HPL is positive in placental site trophoblastic tumors (these tumors can also be focally positive for bHCG)
  • HPL will also stain placental site nodules
  • HPL can identify the implantation site throughout gestation
  
Tissue
  

Submit a formalin-fixed, paraffin-embedded tissue

  

Formalin-fixed, paraffin-embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • Anti - HPL (also known as human chorionic somatomammotropin) identifies intermediate trophoblasts, and syncytiotrophoblasts

Staining pattern

  • Cytoplasmic staining

References

  1. Kurman RJ et al: Immunocytochemical localization of HPL and chorionic gonadotropin in the normal placenta and trophoblastic tumors, with emphasis on intermediate trophoblast and the placental site trophoblastic tumor. Int J Gynecol Pathol 1984;3:101-121.
  
88342 - 1st stain
88341 - each additional stain
  
07/03/2017
  
10/19/2018
  
10/02/2020