Fluphenazine, serum or plasma

Alphabetical Test listing

Fluphenazine, serum or plasma-994

  
Fluphenazine, serum or plasma
  
994
  
LAB994
  
MSO
  
Prolixin
  

Fluphenazine is a phenothiazine derivative (piperazine) used in the treatment of psychotic disorders

  
Serum
  
  
2.0 mL
  
1.0 mL
  

Spin and separate within 45 minutes of specimen collection

  
EDTA plasma
Heparin plasma
  

Lavender (EDTA), 4mL

Dk green heparin (Li or Na), no gel

 

 

  
Ambient (preferred) - 14 days
Refrigerated - 14 days
Frozen - 14 days
  
  • Gel-barrier tube
    • The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.
  
LabCorp Burlington (706887): R-NX
  
Mo - Fr
  
2 - 4 days
  

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

  

Therapeutic: 1.0-10.0 ng/mL

  

Its dose in milligrams equivalent to 100 mg of chlorpromazine is 0.6-1.2 mg. A statistical evaluation1 of clinical studies found the near maximal effective dose of oral fluphenazine to be <6.9 mg/day. For the decanoate, the near-maximal effective dose was 25 mg/two weeks. As a high potency antipsychotic, it may have a high potential for causing extrapyramidal side effects. This would be in addition to the usual adverse effects of antipsychotic drugs (neurologic, anticholinergic, hypotension). Elderly patients should be observed for these occurrences. The half-life of fluphenazine is formulation-dependent. (The decanoate is 5 to 12 days; the hydrochloride 12 to 60 hours.) Fluphenazine is also used to alleviate pain and in childhood development disorders.

  
80342
  
Yes
  
  
Result 3650-9
  
05/29/2019
  
03/25/2020