Aneuploidy 5/9/15 by FISH

Alphabetical Test listing

Aneuploidy 5/9/15 by FISH-4280G (bone marrow) or 4280H (blood)

  
Aneuploidy 5/9/15 by FISH
  
4280G (bone marrow) or 4280H (blood)
  
LAB4280G - CYTOGENETIC BONE MARROW STUDIES
LAB4280H - CYTOGENETIC LEUKEMIC BLOOD STUDIES
  
5/9/15
  
Myeloma
Myeloma FISH panel
Plasma Cell Myeloma
Trisomy 5
Trisomy 9
Trisomy 15
FISH
Fluorescence In Situ Hybridization
  

Gains (trisomy) of chromosomes 5, 9 and 15 are recurring abnormalities in plasma cell dyscrasia disorders including Plasma Cell Myeloma.  According to current mSMART 3.0 myeloma  guidelines, a trisomy result is classified as a standard-risk cytogenetics category. 

This test can be ordered individually or as part of a Plasma Cell Dyscrasia FISH Panel. See the individual panel test for more details.

  
Bone Marrow aspirate
  

Bone marrow aspirate:

Collect bone marrow aspirate in a sterile Sodium heparin (Na hep) syringe and transfer to a sterile vial/tube

  

- or -

  1. Collect bone marrow in sterile syringe (non-heparinized) and transfer to a Dk green Sodium heparin (Na hep), no gel
  2. Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times, to prevent clotting

  
5 mL
  
3 mL
  

Transfer aspirate from syringe to transport container. 

  

Submit entire specimen unspun.  Specimen will be CD138 enriched for plasma cell isolation

  

Sterile vial/tube

  

or

Dk green Sodium heparin (Na hep), no gel

  
Bone Marrow Core
Whole blood
Touch Prep Slides
  

Bone Marrow Core:

Submit in sterile tube/cup filled with sterile culture medium, sterile Hanks Balance Salt Solution (HBSS) or sterile saline

or 

Whole blood:

Dk green Sodium heparin (Na hep), no gel

  
Bone marrow: 10 mm
Whole blood: 5 mL
  

Immediately following collection, mix sample thoroughly by gently inverting 8 - 10 times to prevent clotting.

  

Submit entire specimen.

  
  

AHL Cytogenetics Oncology Request

  

Ambient

  
Specimens retained until completion of all testing
  
  • Improper label (unlabeled or mislabeled)
  • Wrong container (anticoagulant or solution)
  • Delay in transport
  • Improper storage
  • Leaking container
  • Slides broken beyond repair
  
AHL - Cytogenetics: X
  
Mo - Fr
  
14 business days
  

Fluorescence in situ hybridization (FISH)

  

Normal or Abnormal with interpretation.

 

  
88271 x 3
88275
88291
88299
  
Yes
  
  
03/16/2021
  
10/04/1922