MOC-31 by IHC

Alphabetical Test listing

MOC-31 by IHC-12376 - Technical only, 12379 - Technical & interpretation

  
MOC-31 by IHC
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
  • All IHC stains will include a positive control tissue
  
  • The primary use for this antibody is in distinguishing between epithelial versus mesothelial proliferations. It is one of the best markers currently available in recognizing adenocarcinoma
  • This antibody should be used in a panel (see mesothelioma vs. adenocarcinoma panel)
  
Tissue
  

Submit a formalin-fixed, paraffin embedded tissue block

  

Formalin-fixed, paraffin embedded (FFPE) tissue block

  

FFPE tissue section mounted on a charged, unstained slide

  

Ambient (preferred)

  
  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
  
AHL - Immunohistochemistry
  
Mo - Fr
  
1 - 2 days
  

Immunohistochemical staining and microscopic examination

  

If requested, an interpretive report will be provided

  

Specifications

  • MOC-31 is an antibody directed against a small cell carcinoma cell line
  • It reacts with an epithelial antigen present on most normal and malignant epithelia
  • Reactive mesothelial cells and malignant mesotheliomas show rare expression with this antibody

Staining pattern

  • Membrane based staining

References

  1. Sosolik RC, et al. Anti-MOC-31: a potential addition to the pulmonary adenocarcinoma versus mesothelioma immunohistochemistry panel. Mod Pathol 1997; 10:716-719.
  2. Ordonez NG. The immunohistochemical diagnosis of epithelial mesothelioma. Hum Pathol 1999; 30:313-23.
  3. Ruitenbeek T, et al. Immunocytology of body cavity fluids. MOC031, a monoclonal antibody discriminating between mesothelial and epithelial cells. Arch Pathol Lab Med 1994; 118:265.
  
88342 - 1st stain
88341 - each additional stain
  
07/17/2017
  
10/19/2018
  
10/02/2020