Increased pyruvic acid levels have been associated with diabetes mellitus, vitamin deficiencies, uremia, congestive heart failure, liver diseases, muscular dystrophy, thiamine deficiency, and neoplastic conditions.
Pyruvic acid is useful in assessing oxygen deprivation and provides an index of the severity of circulatory failure.
Patient should be in a fasting and resting state (should not exercise).
Ambient (preferred) - 5 days
Refrigerated - 7 days
Frozen - 7 days
Freeze/thaw cycle - stable x3
Pyruvate - lactate; spectrophotometry
0.3 - 0.7 mg/dL