Increased pyruvic acid levels have been associated with diabetes mellitus, vitamin deficiencies, uremia, congestive heart failure, liver diseases, muscular dystrophy, thiamine deficiency, and neoplastic conditions.
Pyruvic acid is useful in assessing oxygen deprivation and provides an index of the severity of circulatory failure.
Draw blood into chilled gray-top tube.
Transfer vial/tube with cap - 12mL (LabCorp)
Ambient (preferred) - 5 days
Refrigerated - 7 days
Frozen - 7 days
Pyruvate - lactate; spectrophotometry
0.3 - 0.7 mg/dL