All special stains will include a positive control tissue
This procedure is used for the demonstration of nerve fibers and the presence of neurofibrillary tangles and senile plaques in Alzheimer disease.
As aging occurs, most individuals develop alteration of neurofibrils in at least some neurons; the neurofibrils may become clumped or twisted. In Alzheimer disease, tremendous numbers of the neurofibrillary tangles develop.
Prepare a formalin-fixed, paraffin-embedded (FFPE) tissue block
FFPE tissue block
Prepare two (2) 8 micron thick section unstained positively charged slides from an FFPE tissue block
Histopathology Processing & Special Stains requisition
Protect paraffin block and/or slides from excessive heat
Histochemical staining and microscopic evaluation
An interpretive pathology report will be provided for Technical with Interpretation cases.