Bielschowsky Silver stain

Alphabetical Test listing

Bielschowsky Silver stain-12376 - Technical only, 12379 - Technical & interpretation

  
Bielschowsky Silver stain
  
12376 - Technical only, 12379 - Technical & interpretation
  
LAB12376
LAB12379
  
Alzheimer
Nerve fibers
Neurofibrillary tangles
Senile plaques
Special stain
  

All special stains will include a positive control tissue

  

This procedure is used for the demonstration of nerve fibers and the presence of neurofibrillary tangles and senile plaques in Alzheimer disease. 

As aging occurs, most individuals develop alteration of neurofibrils in at least some neurons; the neurofibrils may become clumped or twisted.  In Alzheimer disease, tremendous numbers of the neurofibrillary tangles develop.

  
Tissue
  

Formalin vial/container

  

Prepare a formalin-fixed, paraffin-embedded (FFPE) tissue block

  

FFPE tissue block

  

Prepare two (2) 8 micron thick section unstained positively charged slides from an FFPE tissue block

  
  

Histopathology Processing & Special Stains requisition

  

Ambient

Protect paraffin block and/or slides from excessive heat

  
  • Insufficient tissue in block
  • Mislabeled/Unlabeled block or slides
  • Broken slides
  
AHL - Histology: A
  
Mo - Fr
  
24 - 48 hours
  

Histochemical staining and microscopic evaluation

  

An interpretive pathology report will be provided for Technical with Interpretation cases.

  
88313
  
06/29/2021
  
06/30/2021