Alpha-fetoprotein (AFP), maternal serum

Alphabetical Test listing

Alpha-fetoprotein (AFP), maternal serum-13494

  
Alpha-fetoprotein (AFP), maternal serum
  
13494
  
LAB13494
  
AFPB
  
AFP, maternal serum for Open Spina Bifida
AFP, Maternal Serum
Alpha-Fetoprotein,Maternal Serum for Open Spina Bifida
Maternal Serum Alpha-Fetoprotein
  

Screening test for open neural tube defects. Detects 80% of open spina bifida and 90% of anencephaly.

 

  

This test does not provide screening for Down syndrome or trisomy 18.

  
  • Open spina bifida screening is offered for gestational ages 15.0 - 23.9 weeks
  • Optimal gestational age is 16.0 - 18.9 weeks
  
Serum
  
  
3.0 mL
  
0.5 mL
  

Specimens must be collected before amniocentesis.

Immediatley following collection, mix sample by inverting 5 times

  
  1. Allow blood to clot for a minimum of 30 minutes
  2. Spin within two (2) hours of sample collection

   Pour off is not advised.

  

Gold serum separator (SST) tube

  
  

Ambient (preferred) - 7 days

Refrigerated - 14 days

Frozen - 14 days

Freeze/thaw cycles - stable x 3

  
  • Gross hemolysis
  • Gross lipemia
  • Quantity not sufficient for analysis (QNS) 
  • Improper specimen type
  
LabCorp RTP (010801): R-LC
  
Mo - Sa
  
2 - 6 days
  

Chemiluminescent immunoassay

  

An interpretive report will be provided

  

A positive result means that more diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect is present.

  
82105
  
Yes
  
  
Result UNLOINC
  
04/08/2019
  
10/25/2019
  
01/02/2024