Determines viral phenotype and genotype resistance to four classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), protease inhibitors (PI), and integrase inhibitors (INI).
Collect specimen in three lavender-top (EDTA) tubes
Frozen (strict) – 14 days
Refrigerated - NO
Ambient - NO
Phenotype: polymerase chain reaction (PCR) amplification and viral culture Genotype: polymerase chain reaction (PCR) and DNA sequencing
This assay is a combined assay in which HIV resistance phenotype and HIV resistance genotype is performed.
This test should be used for patients with documented HIV-1 infection and viral loads ≥500 copies/mL. If there is insufficient virus to produce results, HIV-1 RNA quantitation will be performed to confirm viral load, for an additional fee.