MyoD1 by IHC

Alphabetical Test listing

MyoD1 by IHC-12376 - Technical only, 12379 - Technical & interpretation

MyoD1 by IHC
12376 - Technical only, 12379 - Technical & interpretation
Rhabdomyosarcoma marker
  • All IHC stains will include a positive control tissue
  • MyoD1 is present in the majority of rhabdomyosarcomas (RMS), and is a superior marker for the less differentiated RMS
  • Stronger staining has been reported in alveolar vs. embryonal RMS
  • Normal mature skeletal muscle does not express MyoD1

Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • MyoD1 is a myogenic nuclear regulatory protein that is normally expressed during embryogenesis, early in skeletal muscle differentiation
  • Nuclear expression of MyoD1 is restricted to myoblasts of developing skeletal muscle tissue

Staining pattern

  • Nuclear
  • Cytoplasmic staining is non-specific, and should be ignored


  1. Morotti RA et al: Am J Surg Pathol 2006;30:962-968. Sebire NJ et al: J clinPathol 2003;56:412-416.
88342 - 1st stain
88341 - each additional stain