Calcitonin by IHC

Alphabetical Test listing

Calcitonin by IHC-12376 - Technical only, 12379 - Technical & interpretation

Calcitonin by IHC
12376 - Technical only, 12379 - Technical & interpretation
  • All IHC stains will include a positive control tissue

The primary use for this antibody is in identifying the calcitonin production in thyroid (c-cell hyperplasia and medullary carcinoma) as well by other tumors


Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • Calcitonin secretion occurs in normal and neoplastic thyroid, and results in hypocalcemic actions on bone and kidney
  • Calcitonin secretion is usually associated with medullary carcinoma of the thyroid, as well as in C-cell hyperplasia
  • The identification of calcitonin production in c-cell hyperplasia is useful in recognizing familial forms of this disease
  • Calcitonin secretion has also been demonstrated in thymic carcinoids, as well as in breast and lung cancers (such as small cell carcinomas)

 Staining patterns

  • Cytoplasmic based granular activity


  1. Melvin KEWQ et al, N Eng J Med 285:1115-1120, 1970.
  2. DeLellis RA et al, Am J Pathol 72:119-128, 1973
88342 - 1st stain
88341 - each additional stain