Neuron-specific enolase, serum

Alphabetical Test listing

Neuron-specific enolase, serum-8560

Test name:

Test number:

8560

Excellian order number:

LAB8560

Abbreviation:

Ser NSE

Alternate names:

NSE

Useful for:

An aid in the detection and monitoring of neuroendocrine tumors (NETs), particularly those associated with small-cell lung cancer (SCLC)

Specimen type:

Serum

Collection container:

Gold serum separator (SST) tube

Volume:

0.5 mL

Minimum volume:

0.3 mL
Submission of the minimum volume does not allow for repeat testing

Collection instructions:

Immediatley following collection, mix sample by inverting 5 times

Processing instructions:

Allow to clot 30 minutes
Spin within 30 minutes of sample collection

Transport container:

Gold serum separator (SST) tube

Alternate collection container:

Red serum vial/tube, 5 mL

Alternate processing instructions:

Allow sample to clot
Spin within 30 minutes of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Alternate transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Transport and stability:

Refrigerated (preferred) - 7 days

Ambient - 7 days

Frozen - 14 days

Freeze/thaw cycles - stable x3

Reason for rejection:

Hemolysis
Gross icterus
Plasma specimen

Performing lab:

LabCorp (140624): R-LC

Days set up:

TAT:

10 days

Method:

The ThermoFisher/BRAHMS KRYPTOR® assay employs Time-Resolved Amplified Cryptate Emission (TRACE) technology based on a non-radioactive energy transfer between a donor (europium cryptate) and an acceptor (XL665) in a sandwich immunofluorescent format using two mouse monoclonal antibodies.

Reference ranges:

0.0−17.6 ng/mL

CPT codes:

86316

Subject to medical necessity (Y/N):

Yes

LCD/NCD:

Medical necessity

Date created:

04/14/2022

Revised date:

12/21/2023

Review date:

12/21/2023