Neu-N by IHC

Alphabetical Test listing

Neu-N by IHC-12376 - Technical only, 12379 - Technical & Interpretation

Neu-N by IHC
12376 - Technical only, 12379 - Technical & Interpretation
Anti-neuronal nuclei
  • All IHC stains will include a positive control tissue
  • NeuN is used to identify neurons within brain parenchyma when infiltrating glial neoplasms obscure normal brain architecture, hence it can be useful to confirm brain infiltration
  • NeuN may also be useful in confirming neuronal phenotypes in biphenotypic CNS tumors like gangliogliomas
  • Unlike other neuronal markers (synaptophysin, neurofilament), NeuN does not stain the background neuropil
  • It may also be used to help assess cortical neuronal cytoarchitecture in suspected migrational disorders

Submit a formalin-fixed, paraffin embedded tissue block


Formalin-fixed, paraffin embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • NeuN is a neuron-specific nuclear protein, which is present within most neuronal cell types within the central nervous system, spinal cord, and peripheral nervous system including ganglion cells
  • NeuN does not stain Purkinje cells of the cerebellum

 Staining pattern

  • Nuclear


  1. Mullen RJ, Buck CR, Smith AM. NeuN, a neuronal specific nuclear protein in vertebrates. Development 1992;116:201-11
88342 - 1st stain
88341 - each additional stain