Detection of vasoactive intestinal polypeptide producing tumors in patients with chronic diarrheal diseases
Not all patients with the syndrome have increased VIP. Increased VIP can be found in healthy controls and in laxative abusers.
This test should not be requested on patients who have recently received radioactive material 24 hours prior to collection.
Brown screw-cap transfer tube from a Trasylol® collection kit
Frozen (strict) - 14 days
Refrigerated - NO
Ambient - NO
0.0 – 58.8 pg/mL
Hypersecretion of VIP is observed in “pancreatic cholera syndrome,” Verner-Morrison syndrome or the watery diarrhea-hypokalemia-hypochlorhydria (WDHH) syndrome. It is characterized by hypermotility, watery diarrhea syndromes with hypokalemia and hypochlorhydria, dehydration and weakness; these symptoms can be reproduced by VIP. VIP can be secreted by pancreatic or ectopic islet cell tumors, and in islet-cell hyperplasia.