Vasoactive intestinal polypeptide

Alphabetical Test listing

Vasoactive intestinal polypeptide-522

Vasoactive intestinal polypeptide

Detection of vasoactive intestinal polypeptide producing tumors in patients with chronic diarrheal diseases

  • Fasting for at least 8 hours prior to sample collection is required

    Fasting for a blood test

  • This test should not be requested on patients who have recently received radioactive material


EDTA plasma
1.0 mL
0.6 mL

Immediatley following collection, mix sample thoroughly by gentle inverting 8 - 10 times, to prevent clotting

  1. Spin
  2. Transfer plasma to a Screw cap transfer vial/tube (Mayo T465), labelled as EDTA plasma
  3. Freeze

Frozen (strict) - 90 days

Refrigerated - NO

Ambient - NO

3 months
  • Gross hemolysis
  • Gross lipemia
  • Specimens received at ambient or refrigerated temperatures
Mayo Clinic Laboratories (VIP/8150): R-MM
Mo - We
3 - 8 days

Radioimmunoassay (RIA)


< 75 pg/mL


Values above 75 pg/mL may indicate the presence of an enteropancreatic tumor causing hypersecretion of vasoactive intestinal polypeptide (VIP).

Values above 200 pg/mL are strongly suggestive of VIP-producing tumors (VIPoma).

VIPoma is unlikely with a 24-hour stool volume below 700 mL.

Order - 3125-2; Result - 3125-2