Haptoglobin binds hemoglobin which is released during erythrocyte lysis. The haptoglobin/hemoglobin complex is rapidly eliminated from the bloodstream. Increased release of hemoglobin due to intravascular hemolysis results in a reduction in the haptoglobin concentrations, and during severe hemolysis, to complete consumption of the haptoglobin. In children, haptoglobin has lower physiological concentrations and therefore is not suited for hemolysis testing. Haptoglobin is an acute-phase protein which can develop very high levels during inflammatory conditions.
Lt green plasma separator (PST)
Gold serum separator (SST) tube
30 - 215 mg/dL