IgD by IHC

Alphabetical Test listing

IgD by IHC-12376 - Technical only, 12379 - Technical & interpretation

IgD by IHC
12376 - Technical only, 12379 - Technical & interpretation
Anti-human IgD
  • All IHC stains will include a positive control tissue
  • In paraffin tissue, the antibody labels plasma cells with IgD
  • IgD labels B cell lymphocytes in primary follicles
  • In secondary follicles, the staining is in the mantle zone with coarse meshwork of IgD in the germinal centers (this represents immune complexes present on the surface of dendritic reticulum cells

Submit a formalin-fixed, paraffin-embedded tissue


Formalin-fixed, paraffin-embedded (FFPE) tissue block


FFPE tissue section mounted on a charged, unstained slide


Ambient (preferred)

  • Unlabeled/mislabeled block
  • Insufficient tissue
  • Slides broken beyond repair
AHL - Immunohistochemistry
Mo - Fr
1 - 2 days

Immunohistochemical staining and microscopic examination


If requested, an interpretive report will be provided



  • The antibody reacts with the heavy chain (delta chain) of human IgD
  • This antibody labels plasma cells, and various lymphocytes (the later depends on the methodology - i.e. frozen vs. paraffin)

Staining pattern

  • Cytoplasmic (plasma cells) and cell surface membrane (lymphocytes)


  1. Mason DY et al: Blood 1987; 69:836-40.
  2. Falini B et al: Histopathology 1986; 10:671-87.
  3. Erber WN et al: Lancet 1986; 1:761-5.
88342 - 1st stain
88341 - each additional stain