Atomoxetine, Serum or Plasma

Alphabetical Test listing

Atomoxetine, Serum or Plasma-994

Test name:

Test number:

994

Excellian order number:

LAB994

Abbreviation:

MSO

Alternate names:

Strattera

Useful for:

Therapeutic drug management

Patient preparation information:

Trough levels are most reproducible.

Specimen type:

Serum

Collection container:

Red serum vial/tube, 5 mL

Volume:

2 mL

Minimum volume:

0.5 mL

Collection instructions:

Immediately following collection, thoroughly mix sample by gently inverting 5 times

Processing instructions:

Allow sample to clot
Spin within two (2) hours of sample collection
Transfer serum to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as serum

Transport container:

Transfer vial/tube with cap - 12mL (LabCorp)

Alternate specimen type:

Dk green heparin (Li or Na), no gel

Alternate collection container:

Alternate collection instructions:

Immediately after collection, mix tube thoroughly by gentle inversion, 8 - 10 times, to prevent clotting

Alternate processing instructions:

Spin within two (2) hours of sample collection
Transfer plasma to a Transfer vial/tube with cap - 12mL (LabCorp), labelled as the appropriate plasma type

Transport and stability:

Refrigerated (preferred) – 7 days

Ambient – 3 days

Frozen – 6 months

Reason for rejection:

Gel-barrier tubes

Performing lab:

LabCorp (790640): R-LC

Days set up:

1 x week

TAT:

7 - 10 days

Method:

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Reference ranges:

Therapeutic range has not been established. Poor metabolizers of cytochrome P450 2D6 (CYP2D6) substrates may have steady-state atomoxetine concentrations sixfold greater than those of extensive metabolizers.

CPT codes:

80299

Date created:

03/23/2023

Review date:

03/23/2023